Characterization of Some Synthesis Brom-isoflavanone and the Inclusion Compounds with beta-Cyclodextrin

The objectives of this study were to characterize a synthesis brom-isoflavanone (notated IF) with possible pharmacological activities, water insoluble and to examine the potential of beta-cyclodextrin to improve this property and obtain inclusion compounds that were analysed by different techniques: UV-Vis, IR, 1HNMR spectroscopy, thermal analysis. The presence of β-cyclodextrin rises the content of IF in water. The inclusion compounds were prepared by co-precipitation in 1:1 and 1:2 molar ratio substance-β-cyclodextrin. The UVVis, IR, 1HNMR analysis demonstrated the obtaining of inclusion compounds and the thermal analysis show that these compounds are more stable than the parent substance.